Ideological and political course is the key course to carry out the basic task of moral education. Up to now, there have a vague understanding and even a wrong view of the ideological and political course still in some college leaders and ideological and political course teachers. This article sorts out the basic connotation and great significance of running the ideological and political course well, and analyzes it from four aspects: confidence, teachers, teaching methods and cooperation, so as to make a modest theoretical contribution to running the ideological and political course well.