The sample of the research are 31 psychological crisis intervention reports with complete case reports and information. A qualitative research method is used to acquire the observation indexes of interpersonal relationships when a psychological crisis occurs. Main observation indexes of interpersonal relationship during college students’ psychological crisis are: (1) unwillingness to communicate with classmates and no time to exchange with teachers and other students because of academic problems will cause depression and then psychological crisis; (2) bad communication between parents and children; (3) traumatic events in the past,especially childhood trauma;(4)conflicts with teachers and classmates.