This case study presents a college student experiencing severe depression and social anxiety due to intergenerational family conflicts, particularly parental expectations of perfection in pursuing medicine. Through a 12-session integrative intervention combining CBT and attachment theory, the client achieved three key outcomes: (1) Disrupting irrational beliefs of “perfection as necessity” and redefining self-worth through intrinsic growth; (2) Developing practical emotion regulation strategies (e.g., diaphragmatic breathing, reality testing) to manage acute anxiety; and (3) Transforming family dynamics from unidirectional compliance to reciprocal communication, resulting in a PHQ-9 score reduction from 21 to 9 (clinical remission). The case underscores the importance of culturally sensitive, family-inclusive approaches in university mental health services to foster students’ autonomy amid generational tensions.