Mainland Chinese exchange students in Taiwan encounter a new living environment, making adaptation a crucial issue. This study adopts a qualitative approach from the strengths-based perspective of positive psychology to explore the cross-cultural adaptation process and key facilitating factors. In-depth interviews were conducted with 12 mainland Chinese exchange students. The findings indicate that students face three primary sources of stress: academic pressure, interpersonal challenges, and lifestyle changes. Key factors that facilitate adaptation include social support, psychological capital, positive coping strategies, cultural similarity, and prior cross-cultural experiences.