At present, many force majeure factors in the environment are increasingly affecting the normal operation of plenty of enterprises. At the same time, the employees’ psychological changes and pressure controlling are further paid attention to the majority of executives and business owners. Previous studies have found that employees’ attitudes toward work are easily affected by adversity. Under the current background, this study included practical analysis and discussion on six aspects of employees’ emotional stability, family concept, post difference, team harmony, turnover rate and nature of enterprise. TTrough psychological assessment and stress test, 136 employees were invited as data samples to conduct an online questionnaire survey. TTe results showed that: Emotional stability and team harmony can quickly alleviate or reduce employees’ negative psychological attitude to the epidemic, while the other three factors have relatively little impact. However, these studies have a certain limitation on the dimission rate of employees. Employees’ mental health and stress will affect the dimission rate of employees, and too high dimission rate will lead to the decline of the resilience of enterprises and weaken the resilience of enterprises. TTe data results of this study can support the recruitment and employee training plans of enterprises, and put forward management suggestions for employees’ mental health and stress management ability under adversity