The Asperger syndrome has the same social difficulties as autism, limited interests and repetitive, stereotyped patterns of activity, but no apparent language or intellectual impairment, social difficulties are the core problem of the disease. As a child grows older, challenges and dilemmas will follow, making it more difficult for the child to adapt to school and society, and even a variety of behavioral problems, even depression, anxiety and other mental problems. Acceptance and commitment therapy is one of the most representative therapies in the“Third wave” of cognitive behavioral therapy, act helps children to recognize and accept their own emotions, values, and psychological experiences by focusing on the present, thinking for themselves, defining their values, and committing to action, to reduce the experiential avoidance of children, enhance psychological flexibility, help children with a meaningful life. The advent of acceptance-commitment therapy has provided a new orientation for Asperger syndrome intervention.