Post traumatic stress disorder (PTSD) refers to the mental disorder that occurs and persists for a long time after the body encounters an unusual threat or disaster. Its clinical manifestations are mainly characterized by pathological recurrence, continuous increased alertness, continuous avoidance and selective forgetting of traumatic experience. The course of PTSD is prolonged, which seriously affects the psychology and society of patients function. In the increasingly competitive modern society, sudden stress events are increasing day by day, and the occurrence of PTSD shows an obvious upward trend. Therefore, how to prevent the occurrence of PTSD, especially how to prevent the occurrence of PTSD, is particularly important. This paper focuses on the psychological mechanism, treatment of post-traumatic stress disorder and research the prospect.