Objective: In order to identify students who are likely to have mental health crisis in the near future, a rapid mental health crisis screening system was developed to test the validity and reliability of the Long-term Risk Scale, the Short-term Risk Scale and the Exinanition Illness Scale in a sample of college students and to assess the effectiveness of the rapid mental health crisis screening system in predicting suicide risk among college students. Methods: The mental health crisis rapid screening system was used to administer the Long-Term Risk Scale, the Short-Term Risk Scale, the Exinanition Illness Scale, and the Beck Depression Inventory to a sample of college freshmen. Results: The internal consistency coefficient of the Long-Term Risk Scale was 0.601, the correlation with the total score of the Beck Depression Inventory was 0.423 (p<0.01), and the retest correlation coefficient was 0.727 (p<0.01). The internal consistency coefficient of the Short-Term Risk Prediction Scale was 0.829, and the correlation with the total score of the Beck Depression Inventory was 0.652 (p<0.01). The internal consistency coefficient of the Exinanition Illness Scale was 0.872, the correlation with the total score of the Beck Depression Inventory was 0.578 (p<0.01), and the retest correlation coefficient was 0.644 (p<0.01). The area under the ROC curve for the Long-Term Risk Scale, the Short-Term Risk Scale, the Exinanition Illness Scale, and the Beck Depression Scale ranged from 0.770 to 0.851. Among the 14 high-risk cases, the Long-Term Risk Scale was able to predict an additional 2/2/2 cases, the Short-term Risk Scale was able to predict an additional 1/4/2 cases, and the Exinanition Illness Scale was able to predict an additional 1/3/3 cases compared to the Beck Depression Inventory, using 1, 2, and 3 standard deviations from the mean of each scale. The prediction rate of the mental health crisis rapid screening system for crisis cases was 92.9%. Conclusion: (1) The Long-Term Risk Scale, the Short-Term Risk Scale, and the Exinanition Illness Scale have good reliability and validity in the college student sample; (2) Compared with the Beck Depression Inventory, the mental health crisis rapid screening system has relatively better prediction of suicide risk and can contribute specific predictive individuals, which can quickly identify students who may have mental health crisis in recent times and in the future and pay close attenftion to them.