Bipolar disorder is indeed a common and serious mental illness in the contemporary world, especially among adolescents. It is extremely important to clarify the psychopathological mechanism of bipolar disorder. Only by understanding the formation of bipolar disorder, can it play a key role in the prevention and treatment of bipolar disorder, and in reducing patients' pain and other clinical aspects. Therefore, this review focuses on the physiological, psychological and social aspects, as well as the integrated model of abnormal psychology. Collect and integrate the literature in recent years and some classical literature research in earlier period, and review the psychopathological mechanism of bipolar disorder with my own thinking, and put forward the corresponding treatment plan on this basis.