This paper mainly expounds the contents, methods, existing problems and solutions of college counselors in carrying out mental health work. College counselors’ mental health work involves the following aspects: ideal, faith and values, lack of life goals, interpersonal problems, love and sexual psychological problems, personality and emotional problems, career planning and employment psychology. The way to carry out mental health work mainly lies in integrating psychological theory and individual group in daily work. The work still needs to be considered from the ways of improving the professional quality of psychological counseling, improving the ability to deal with psychological crisis and using peer resources.