Objective: The national comprehensive fire and rescue team is the main force of emergency rescue, and increasing the positive psychological resources of firefighters can improve the ability to resist stress risks. This study explored the relationship between firefighters’ self-compassion, perceived social support, and subjective well-being. It provides an empirical reference for improving firefighters’ subjective well-being through self-compassion. Methods: The study uses a sample of 516 firefighters from four firefighting teams in the southwestern region of China, who complete self-compassion scale, multidimensional scale of perceived social support, life satisfaction and positive and negative emotion scale. The study uses ANOVA, correlation analysis, regression analysis, and Bootstrap test to investigate the relationship between self-compassion, perceived social support, and subjective well-being among firefighters. Results: (1) ANOVA shows that perceived social support and subjective well-being are significantly different in terms of marital status and job positions, with front-line combatants being higher than those in the administrative units, and unmarried firefighters being higher than married firefighters.(2) Correlation analysis shows that self-compassion is significantly positively correlated with perceived social support and subjective well-being (p<0.01).(3) Regression analysis shows that firefighters’ self-compassion can significantly predict subjective well-being (β =0.46, p<0.001) , and perceived social support can significantly predict subjective well-being (β =0.37, p<0.001).(4) The results of the Bootstrap test show that the direct effect of self-compassion on firefighters’ subjective well-being is significant, with a direct effect value of 0.47, accounting for 74.60%. The mediating effect of perceived social support on self-compassion and subjective well-being was significant, with a mediating effect value of 0.16, accounting for 25.40%. Perceived social support played a partial mediating role in the relationship between self-compassion and subjective well-being. Conclusion: Self-compassion can be indirectly enhanced through perceived social support, thereby improving firefighters’ subjective well-being. In the daily training of firefighters, self-compassion training can be increased to enhance firefighters’ ability to perceive social support, thereby improving their subjective well-being and promoting quality of life.