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抑郁症患者抑郁情绪对认知功能影响的研究进展

Research Progress on the Effect of Depression on Cognitive Function in Patients with Depression

Psychology of China / 2024,6(12)：2293-2299 / 2024-12-30 162 104

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• Authors: 庞鹤      王英      李德翼      栾研霏      何珊      毛雨蓓      梅小越      谢维      熊富勇      肖安建      张介平     
• Information:

  西南医科大学人文与管理学院，泸州

• Keywords: 抑郁情绪；认知功能障碍；影响因素；机制；相互关系
• Depression; Cognitive impairment; Influencing factors; Mechanisms; Interrelationships
• Abstract: 目前，大多数研究表明抑郁症患者存在认知功能障碍，且抑郁情绪与认知受损存在一定的相关性。认知功能障碍具有一定的特征性表现，可表现在执行功能、注意力，以及记忆功能障碍等方面。同时，抑郁情绪对认知功能的损害涉及到一些相关的影响因素，如年龄、病程、发病次数以及严重程度等。其间，可能存在的机制可包括：海马功能受损、神经细胞凋亡与脑组织萎缩、额—顶叶神经回路以及默认模式网络等方面。最后，着重探讨了揭示抑郁情绪与认知障碍之间相互关系的相关研究，可为今后对抑郁患者认知功能障碍的干预提供一定的参考。
• At present, most studies have shown that patients with depression have cognitive impairment, and there is a certain correlation between depression and cognitive impairment. Cognitive dysfunction has certain characteristic manifestations, such as executive function, attention and memory dysfunction. At the same time, the damage of depression to cognitive function involves some related factors, such as age, course of disease, frequency of onset and severity. Among them, the possible mechanisms may include hippocampal dysfunction, neuronal apoptosis and brain atrophy, frontoparietal neural circuits and default mode networks. Finally, it focuses on revealing suppression. The study on the relationship between depression and cognitive impairment can provide some reference for the intervention of cognitive dysfunction in depressive patients in the future.
• DOI: https://doi.org/10.35534/pc.0612263
• Cite: 庞鹤，王英，李德翼，等．抑郁症患者抑郁情绪对认知功能影响的研究进展［J］．中国心理学前沿，2024，6（12）：2293-2299．