Objective: Through understanding the current situation of aesthetic education of medical college students and combining the characteristics of schools and students, a systematic aesthetic education activity system is constructed to implement the school aesthetic education infiltration action, and widely carry out popular, diverse, rich and positive aesthetic education practice activities. Methods: By random sampling, 526 students from Baotou Medical College were selected as the research objects. Results: More than 95% of college students believe that aesthetic education is important and have a clear understanding of aesthetic education; in the process of developing aesthetic education activities, there are some problems such as boring content, single form and insufficient innovation; a variety of aesthetic education activities is an important measure of aesthetic education. Conclusion; The design of aesthetic education activities in medical colleges should meet students’ reality, further digging aesthetic education materials and carry out rich and colorful aesthetic education activities.