This paper examines the current situation of psychological distress among poor collegestudents, and the role of core self-evaluation in the relationship between class mobility perception andpsychological distress, so as to provide relevant basis and measures for intervention and solution to thepsychological distress of poor students. Methods: The Class Mobility Perception Scale, the PsychologicalDistress Scale and the Core Self-Evaluation Scale were used to investigate the current situation ofpsychological distress among college students. Results: (1) There was a significant positive correlationbetween class mobility perception and psychological distress (r=0.234, p<0.05). That is, the strongerthe perception of class mobility, the deeper the degree of psychological distress. The perceived positiveprediction of class mobility was the core self-evaluation (r=0.362, p<0.05). That is, the stronger theperception of class mobility among poor students, the higher their core self-evaluation. There was asignificant positive correlation between core self-assessment and psychological distress (r=0.53, p<0.05).(2) The results of the mediating effect show that the core self-evaluation plays a partial mediating rolein the role of class mobility perception on the psychological distress of poor students. Conclusion: Thehigher the core self-evaluation, the deeper the degree of psychological distress. Core self-evaluation canhelp predict the impact of perceived class mobility on the psychological distress of poor students.