Deception is an important means and skill of social communication. Previous studies have found that individuals with autism spectrum disorders (ASDs) are generally difficult to acquire this skill, which seriously affects their quality of social life. Deception often involves executive function and reward processing. Therefore, the impairment of executive function and reward processing may be the main reason why ASD individuals are difficult to deceive. Future research should explore the relationship between deception injury and executive function and reward processing ability of individuals with ASD and its neural mechanism, and provide targeted interventions to promote socialization of individuals with ASD.