The Survivor guilt is an unique guilt. In the context of disasters, The survivors during disasters with guilty emotion is used to describe the feelings of people who have experienced events such as war or natural disasters. Some researchers suggests that Who have survived from the disasters often feel guilty. Survivor Guilt is a special form of guilt, so we can use common measurement of guilt to evaluate it. It mainly includes self-report, situational / episodic emotional measurement, brain imaging technology and so on. Generally the generation of guilt relates to two kinds of factors: personal characteristics and situational factors. Empathy, attribution and evaluation style will have a major influence on survivor guilt. Survivor guilt may bring many negative effects to the individuals. Some researchers have proposed that post-traumatic survivors tend to develop the guilty behavior modes. Such as alexithymia, social avoidance, irritability, self-deprecation, etc, resulting in a variety of physical and psychological problems. However, on the other hand, due to the interpersonal nature of survivor guilt, it can improve the group cohesion and promote the altruistic behaviors, and it will urge individuals to apologize, compensate and other prosocial behaviors. Although some non-specific interventions have been used, there is no specific intervention methods to alleviate survivor guilt. Evidence-based treatments for PTSD such as Prolonged Exposure Therapy (PE) can help individuals successfully process traumatic guilt, but not all studies support this conclusion. At present, cognitive therapy is the key point of our intervention, because cognitive factors play an important role in the generation of guilt. In general, there are a lack of targeted research on survivors guilt, we suggest to consider the following aspects comprehensively: research on the survivors guilt in the public health event; cross-cultural research on the survivors guilt; study the mechanism of survivors guilt.