With the development of the integration of industry and education, exploring the dynamic mechanism of collaborative innovation between higher vocational colleges and enterprises has become the key to improve school-enterprise cooperation. This paper reviews the concept of collaborative innovation and its application in higher vocational education, analyzes the constraints on school-enterprise collaborative innovation caused by problems such as imperfect policy environment, lack of management mechanism, closed and outdated schoolrunning philosophy, disconnection between teaching and production, weak faculty and lack of enterprise cognition, and puts forward the strategy of renewing school-running philosophy to promote the participation of all employees in collaborative innovation. Build a way to strengthen the connection between schools and enterprises and deepen the basic path of connotation construction.