With the rapid development of science and technology, a new teaching mode of “Internet + higher education” has been gradually formed. To solve the teaching problem of the time series course, this paper explores the application of mixed teaching mode. Based on the characteristics of the time series course, this paper adopts the online and offline blended teaching pattern about “Internet +flipped classroom”, which can promote students’ active learning, improve their learning interest, guide their innovative thinking and cultivate their practical and teamwork abilities.