Under the background of “00” students in higher vocational schools, this paper analyzes the current situation, pain points and causes of “student-centered” classroom reform in higher vocational schools, integrates the academic theories of constructivism and Brunard structuralism of scholars such as Piaget and Lev Vygotsky, and combines the research of Wang Jue based on learning science to take the teaching innovation of “Crop Cultivation” as an example. In terms of textbook content, it innovates from three aspects: reconstruction of curriculum content, expansion of curriculum resources and construction of curriculum ideology and politics. In the presentation of classroom teaching, the “three modernization” of this course is constructed from “semantic situational”, four measures are strengthened specifically, and the integrated strategy of “teaching, learning, training, doing and evaluation” is continuously optimized. In the application of teaching methods, it explores the BOPPPS teaching model, the innovative teaching model of classroom, PBL and group training, so as to explore and make up for the shortcomings of “student-centered” constructivism and structuralism education and teaching theory in the application of higher vocational teaching, and promote the common progress and development of teachers and students in higher vocational education.