With the continuous advancement of the new curriculum reform of physics and quality education, the instructional design of physics classroom should also keep pace with the times and constantly update to meet the requirements of the new curriculum reform. This paper discusses the basic strategies of junior high school physics instructional,design based on the new curriculum concept, and takes “the relationship between fluid pressure and flow velocity” as an example to put forward specific instructional design, in order to provide some reference for cultivating students’ physical core literacy and improving the effect of junior high school physics teaching.