This paper mainly summarizes the practical experience and exploration of using engineering case teaching method in the course of Chemical Safety and Environmental Protection. This paper expounds three forms of engineering cases: practical training operation, imitation of real training, video animation, the specific application of teaching methods in the classroom, and proposes to dig as many as possible engineering cases from the relevant enterprises in the region, to enrich the case library. In engineering case teaching, teachers use engineering case as the guidance, actively encourage students to become independent explorers of knowledge, summarize engineering practical experience, and provide favorable support for the future safety and environmental protection industry in the chemical industry.