Concrete Structure Course is a theory-oriented and practice-oriented course, which is rich in content, rigorous in theory and strong in application, and plays an important role in cultivating students’professional theory level and practical application ability. The traditional teaching method can hardly meet the teaching demand of the course, but the reform of the student-centered integrated teaching mode overturns the traditional teaching and tries to arouse the students’ interest in exploring the unknown things, cultivate students’ comprehensive ability of self-study, teamwork and problem-solving. Taking the teaching of “concrete structure” as an example, this paper sums up the student-centered integrated teaching model, which combines the information teaching methods of MOOC, SPOC, overturned class and rain class, etc. at the same time, the concrete implementation methods and suggestions are given in order to provide some references for the teaching reform of higher education.