The rapid surge of the large language models represented by ChatGPT has stricken the translation industry since 2023, providing new possibilities for the improvement of artificial intelligence translation technology. Designing the specific Prompts and clarifying the translation task based on the intractability of ChatGPT can effectively improve the translation quality and ChatGPT’s practicability by stimulating the its potential. The study introduces six design thinking of Prompts and selects sample texts for experiments to explore the effects of different Prompts on the translation effectiveness of ChatGPT.