Role of MicroRNA in Muscle Atrophy and Exercise adaption

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microRNA与肌萎缩及运动的影响

Study on China Physical Science / 2021,3(1): 99-106 / 2021-03-17 look

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Authors: 张淑芳
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武汉体育学院研究生院，武汉
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Keywords: miRNA；分化与增值；肌萎缩；运动
miRNA; Proliferation and differentiation; Muscle atophy; Exercise
Abstract: 骨骼肌占人体重量的 40%-50%，是控制机体代谢的主要组织，并执行人体行走、代谢和呼吸运动的功能。骨骼肌生长和发育是一个高度有组织的过程，因此，对这些过程进行调节的机制是非常复杂的。最近研究发现，microRNA 在骨骼肌生长、发育和代谢等各个方面发挥着非常显著地作用。本文总结了 miRNA 在肌肉生成、肌萎缩和肌肉老化等各个方面的最新研究进展。
Skeletal muscle comprises approximately 40% of body weight, and is important for locomotion, as well as for metabolic homeostasis. Skeletal muscle growth and regeneration are highly organized processes thus it is not surprising that a high degree of complexity exists in the regulation of these processes. Recently, growing evidence indicates that microRNAs significantly impact muscle growth, regeneration and metabolism. In this review, recent advancements in miRNA function during myogenesis, atrophy, aging, exercise are discussed.
DOI: https://doi.org/10.35534/scps.0301009
Cite: 张淑芳．microRNA 与肌萎缩及运动的影响［J］．中国体育研究，2021，3（1）：99-106． https://doi.org/10.35534/scps.0301009