OBJECTIVE To let the hospital pharmacists know the implementation method of the system commenting on traditional Chinese medicine prescription, to understand the common quality problems of traditional Chinese medicine prescription and the measure intervention and improvement of prescription quality. METHODS According to the requirement of traditional Chinese medicine prescription quality control, with the practice of author's many years of commenting on traditional Chinese medicine prescription, put forward Implementation the system commenting on prescription and the measure intervention and improvement of prescription quality. RESULTS The Implementation of the system commenting on traditional Chinese medicine prescription is practical, the improvement can solve the problems of traditional Chinese medicine prescription quality. CONCLUSION The author's measure intervention and improvement of traditional Chinese medicine prescription quality can provide reference for pharmacists commenting on prescriptions and examining or verifying prescriptions.