Objective: to understand the clinical manifestations of side effects of antituberculosis drugs in the course of treatment. Methods:56 patients with antituberculosis drugs were treated and nursed in time to relieve the tension factors. Results:56 cases of adverse reactions were cured after effective treatment. Conclusion: the indications and contraindications of antituberculous drugs are strictly controlled, the toxic and side effects of various drugs of Dendrobium are showed, and regular reexamination is strictly carried out, so as to facilitate early diagnosis, early treatment and improve the cure rate of primary disease.