Industry is the core and foundation of urban development, and promoting urban industrial upgrading is an important measure to implement the national high-quality development strategy. This article closely follows the connotation of urban-rural integration policies and is based on the actual economic and social development of Cangzhou City. It will deeply explore resource endowments, focus on building high-end products, deepen coordinated urban-rural development, and give full play to the dual engine role of government and market as an important path to promote industrial upgrading in Cangzhou, in order to provide effective reference for policy planning and formulation in Cangzhou.