In order to meet the requirements of data processing ability in thebig data era, this paper proposes a mixed classification teaching method forPython courses according to the advantages of Python programming languageand the characteristics of students’ disciplines. This paper mainly discussesthe content of mixed classification teaching mode, the teaching status ofPython course and the necessity of mixed classification teaching, and finallyanalyzes the design scheme of mixed classification teaching. In the mixedteaching mode, the teaching process of “Preview - Theoretical Study - PracticalStudy - summary and reflection” is put forward. In the classified teaching, theprocess of the classified teaching method is explained by the case method. Theimplementation of mixed classification teaching method can not only trainstudents to independently use Python to develop programs, but also improvetheir computer application level. It can also effectively improve teachingefficiency and quality.