By using the methods of literature, questionnaire survey and teaching experiment, this paper discusses the influence of 8-week PE game teaching experiment intervention on the interest of higher vocational students in PE learning, and provides some theoretical reference for improving the physical health of higher vocational students and PE teaching. The results showed as follows: (1) Through the 8-week sports game teaching experiment intervention, the students’ interest in sports learning was significantly improved in the experimental class, while the students’ interest in sports learning in the control class was not significantly different before and after the experiment. (2) By intra-group comparison, the experimental classes had significant differences in the three dimensions of extracurricular activities, enthusiasm and skill learning, but no significant differences in the two dimensions of negativity and sports attention. There was no significant difference in negativity, extracurricular activities, enthusiasm and skill learning in the control class. (3) Sports games are entertaining, competitive and educational. The introduction of sports games into sports teaching can stimulate students’ interest in sports learning, enrich teaching content and improve teaching quality, which is an important content to help the cause of physical education.