In order to explore the influence of popular dance practice on physical self-esteem and appearance anxiety of contemporary female college students, 86 female college students were investigated by Physical Self-esteem Scale (PSPP) and Social Appearance Anxiety Scale (SAAS). Pearson correlation analysis and SPSS Hayes' PROCESS were used to test the correlation and mediating effect. The results showed: 1)Appearance anxiety was significantly related to the popular dance practice time(r=-0.394, p=0.003), physical self-esteem(r=-0.337, p=0.014), PSW(r=-0.389, p=0.004), PC(r=-0.461, p=0.001), and AB(r=-0.317, p=0.021)dimensions in physical self-esteem negative correlation;2)Physical self-esteem was positively correlated with the duration of pop dance practice time;3)The results of the mediating effect test showed that physical self-esteem had a significant positive predictive effect on the popular dance practice time (B=0.4032, p=0.0028) and the popular dance practice time had a significant negative predictive effect on appearance anxiety (B=-0.3085, p=0.0308). And when the popular dance practice time was used as a mediating variable, the direct effect of the model was not significant(p=0.1314), but the total effect (B=-0.4501, p=0.013<0.05, t=-2.558) and the mediating effect (B=-0.1660, Boot LLCI=-0.3803, Boot ULCI=-0.0250) was significant. It indicates that in this model, the popular dance practice time plays a fully mediating role, and the mediating effect accounts for 36.8% of the total effect. Conclusion: Female college students' Physical self-esteem affects appearance anxiety through the mediating effect of the popular dance practice time.