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多例胰岛细胞瘤临床诊治报告

Clinical diagnosis and treatment of several cases of islet cell tumor

临床医学前沿 / 2019,1(1)：12-17 / 2019-12-27 664 712

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• 作者： 丁维      黄安明     
• 单位：

  滨州医学院附属医院，滨州 

• 关键词： 胰岛细胞瘤；胰岛素瘤；临床
• Islet cell tumor; Insulinoma; Clinical
• 摘要： 目的：探讨胰岛细胞瘤的临床特征、治疗方法。方法：对我院 2014 年 到 2018 年收治的 12 例胰岛细胞瘤的临床表现、检查方法和治疗结果进行回顾 分析。结果：本组经手术切除病理证实胰岛素瘤 11 例，恶性非功能性胰岛细胞 瘤 1 例。肿瘤位置：胰头 1 例，胰颈 3 例，胰体 4 例，胰体尾交界处 4 例，胰 尾 2 例。12 例均施行手术治疗，行胰体尾切除术 5 例，肿瘤局部切除术 7 例。 功能性胰岛细胞瘤术后血糖上升为 5.5 ～ 11mmol/L，非功能性胰岛细胞瘤患者 术后腹痛症状消失。12 例均治愈出院，无手术死亡。结论：胰岛细胞瘤主要是 胰岛素瘤和无功能胰岛细胞瘤，可行单纯肿瘤切除或胰腺部分切除。
• Objective: to investigate the clinical features and treatment of islet cell tumor. Methods: the clinical manifestations, examination methods and treatment results of 12 cases of islet cell tumor admitted to our hospital from 2014 to 2018 were retrospectively analyzed. Results: 11 cases of insulinoma and 1 case of malignant non- functional islet cell tumor were confirmed by surgery and pathology. Tumor location: 1 case of pancreatic head, 3 cases of pancreatic neck, 4 cases of pancreatic body, 4 cases of pancreatic body and tail junction, 2 cases of pancreatic tail. All 12 patients underwent surgical treatment, including 5 patients who underwent pancreaticotailectomy and 7 patients who underwent local tumor resection. Postoperatively, the blood glucose of patients with functional islet cell tumor increased to 5.5-11 mmol/L, and the symptoms of abdominal pain of patients with non-functional islet cell tumor disappeared. All 12 cases were cured and discharged from hospital without death. Conclusion: islet cell tumor is mainly insulinoma and nonfunctional islet cell tumor.
• DOI： https://doi.org/10.35534/fcm.0101003c
• 引用： 丁维，黄安明．多例胰岛细胞瘤临床诊治报告［J］．临床医学前沿，2019，1（1）：12-17．