Compared with the diseases in any organ of the human body, the abnormal brain are complex and unfathomable. This is not only due to the limited means to explore the human brain, but also the human body's mental activities are not only restricted by its own biological laws, but also regulated by the external natural and social environment. So far, people's understanding of mental disorders is still in a state of scratch, especially the three most important clinical scientific problems of its pathogenic mechanism, objective diagnosis and efficient treatment have not yet made a key breakthrough.