As an important node city in the coordinated development of Beijing, Tianjin and Hebei Province, Shijiazhuang is also the political, economic, cultural and scientific center of Hebei Province. The spatio-temporal variation of vegetation coverage can well reflect the green development status of the city. This paper selects Landsat series data, calculates the normalized vegetation index, and combines the pixel dichotomy, a remote sensing estimation model, to study the spatial-temporal changes of vegetation coverage in Shijiazhuang from 2016 to 2022. The results show that the vegetation cover in Shijiazhuang decreased significantly from 2016 to 2019, and tended to be stable from 2019 to 2022. The area of high vegetation cover decreased by 3474.64km², the area of high vegetation cover increased by 1228.68km², the area of medium vegetation cover increased by 993.5km², and the area of low vegetation cover and low vegetation cover also increased by 648.77km² and 603.69km², respectively. In space, it is high in the west and low in the east. The study of spatiotemporal variation of vegetation coverage in Shijiazhuang provides a scientific reference for the further green development of the city.