This paper summarizes the fire prevention and extinguishing technology in coal mine, mainly analyzes the classification, cause, harm and prevention technology of mine fire. Coal mine fire is mainly divided into two categories according to the cause of fire, internal fire and external fire, of which internal fire accounts for a relatively high proportion, usually caused by spontaneous combustion of coal seam, also known as spontaneous combustion fire. This paper discusses the mechanism, condition and influencing factors of coal spontaneous combustion in detail, and introduces the test method of coal spontaneous combustion tendency. Further, the paper systematically sorted out the common fire prevention technology, including filling and plugging, pressure equalization, grouting, inert gas, retarder, polymer material, three-phase foam, etc., and discussed the fire fighting mechanism, advantages and disadvantages and applicable conditions of these technologies. Finally, the paper emphasizes the seriousness and importance of China’s coal mine safety work, and points out the direction of future technology development.