At present, the drug situation in the world is constantly evolving, and drug crime is full of tricks. Withthe pace of digitization, the drug trade is moving towards the darknet space, which also continuously extends thedrug crime industry chain, making illegal acts wander in the black and gray areas. The black and gray industry ofdrug crimes on the darknet is a three-dimensional interweaving of legal and illegal, and constantly “pushes” forthe crime, which urgently needs to be combated and governed. Therefore, on the basis of the realistic backgroundand literature analysis, this research objective is placed at the level of strategic research for dynamic analysis andexploration, and SWOT analysis is innovatively applied to assess the strengths, weaknesses, opportunities andthreats of the whole-chain governance, and multi-dimensionally put forward strategic choices for the governanceof the black and gray industry of dark-network drug crimes through organic combinations with a view torealizing the principle of “exerting and utilizing the strengths, overcoming the weaknesses and vulnerabilities,and taking advantage of the strengths, and overcoming the weaknesses and vulnerabilities”. Utilizing strengths,overcoming weaknesses and vulnerabilities, exploring and capturing opportunities, and resolving and avoidingthreats", further curbing the growth of the dark-network drug crime black and gray industry, and strengtheningthe scientific governance of the dark-network drug crime black and gray industry.