Currently, crimes against citizens' personal information are increasing, and personal information security is facing more serious challenges. [ Xie Junsi, "More than 33,000 cases of crimes against citizens' personal information detected," in People's Public Security Daily, January 15, 2022, p. 004]. The rapid development of the digital economy has made the economic, mobile, convergent, and industrialized characteristics of citizens' personal information more prominent, and has also highlighted the importance of protecting citizens' personal information security. New ways and forms of collecting, processing and using citizens' personal information are emerging, and whether the collection, processing and use of personal information, such as big data killing, deep forgery and health code, which are always and everywhere, are infringements of citizens' personal information needs to be judged by digital economy thinking. Digitalization is the trend of the times, and it is impossible for the criminal law to protect citizens' personal information to avoid this trend of the times, but can only adapt to the situation in the context of the digital economy and adapt to the protection of citizens' personal information in the context of the digital economy through the adaptation of the crime of infringement of citizens' personal information. This paper intends to explore the new role of criminal law in protecting citizens' personal information security in the era of digital economy from the perspective of the adaptation of the crime of infringement of citizens' personal information.