In the face of a series of problems existing in the judicial practice of forensic science, such as the entrusting link of appraisal highlights objectivity and impartiality and lacks the ability to screen, the implementation link pays attention to efficiency and lacks procedural supervision; the appraiser in the crossexamination link often evades the cognitive ability of judges and lawyers with the help of the halo of scientific evidence and the use of “polysemy”; judges rely too much on the scientific nature of expert opinions, and so on. For this reason, the innovative application of econometric statistics to unveil the “veil” of forensic science and interpret the law and meaning of forensic science is an effective way to improve judges’ cognitive ability of expert opinions. Combined with the current situation of forensic science research at home and abroad, starting from the basic theory and practical research of econometric statistics, with the help of “quantitative evaluation”, “Bayesian reasoning” and other model theories, this paper puts forward the idea of constructing a “econometric statistical analysis model” of forensic science, taking econometric statistics as a link to promote the benign mutual development of forensic science and evidence law, and further promote the development and construction of the comprehensive service information platform of forensic science. Break the limitation of econometric statistics in the field of economics, optimize the examination mechanism of judges’ appraisal opinions to the maximum, improve their understanding ability of forensic science, and strive to break the new breakthrough of forensic science in the field of econometric statistics, so as to provide a reference path for promoting the high-quality development of forensic science.