Drug-related cases have great harm and hard to get clues. Phone data is an important evidence in drug-related case investigation. This paper base on suspect’s phone data, introduces how to establish a drug-related intelligence clue mining model, apply big data analysis technology such as knowledge map, construct virtual identity relationship network of drug-related groups, analyze and mine potential drug-related clues, realize the conversion from data to clues, and provide valuable clues for drug-related case investigation.