Information technology is a kind of activity which takes data and information as the object, takes computer technology, Internet technology, multimedia technology and other combined application as means to effectively deal with practical problems. Therefore, information engineering cannot do without the support of mathematical theory and method. In the process of information development, the scientific application of applied mathematics plays an important role. In this regard, the study of Applied Mathematics to promote the application of information technology is of great significance. Based on this, starting from the overview of Applied Mathematics and informatization application, this paper briefly analyzes the application performance of Applied Mathematics in the field of informatization, and clearly points out the promotion effect of Applied Mathematics on the development of informatization.